Acrylink MPLN is a nucleic acid anchoring reagent for expansion microscopy, designed to covalently link endogenous DNA and RNA to the hydrogel.
Its nitrogen mustard-based chemistry reacts with nucleic acid bases, while a polymerisable group enables incorporation into the gel. By anchoring the nucleic acids themselves, Acrylink MPLN supports their retention rather than relying solely on the retention of detection probes.
This chemistry provides an anchoring step for workflows investigating the spatial organisation of DNA and RNA in expanded samples. Visualisation is achieved using the staining or detection method selected for the experiment.
Available sizes
• Small (S): 1 mg
• Medium (M): 5 mg
• Large (L): 10 mg
