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Membrane ExM
Reagents for Membrane visualization in ExM
Membrane ExM reagents are designed for the direct staining and retention of cellular membranes in Expansion Microscopy workflows. These functionalized lipid probes insert into biological membranes and carry a polymerizable acrylate group, ensuring covalent anchoring into the hydrogel during gelation. This design preserves delicate membrane architecture through digestion and isotropic expansion, enabling clear, nanoscale visualization with standard fluorescence microscopes.
The product range includes multiple dye variants optimized for different staining needs: the 405 nm variant provides broad, uniform staining of cellular membranes, while other charged dye variants show a slight preference for organelle membranes, enhancing contrast for intracellular structures. For researchers seeking flexible workflows, Membrane ExM Post products enable broad membrane staining after gelation and expansion, ensuring strong signal retention with minimal background.