Protein & Antibody Labelling
Bring protein localisation into focus. Explore conjugation and anchoring chemistry for preparing proteins and antibodies for expansion microscopy.
Connecting molecular recognition with imaging
Where a protein is located can be as informative as its presence. Antibody-based imaging connects molecular recognition with spatial information, allowing researchers to investigate the distribution of selected targets within cells and tissues.
Preparing these labels for expansion microscopy adds another requirement: the information they mark must remain connected to the hydrogel during processing. Antibody-conjugation reagents can introduce both detection functionality and a polymerisable group, while amine-reactive linkers provide a route for attaching anchoring groups to proteins and antibodies.
The appropriate preparation depends on the role of the reagent in your experiment. You may need a fluorescent conjugate for direct detection, a reactive handle for subsequent labelling, or anchoring chemistry for an existing protein or antibody preparation.
Why choose Chrometra?
Labelling and anchoring together
Antibody-conjugation reagents combine detection functionality with a polymerisable group, preparing conjugates for incorporation into the expansion gel.
Chemistry for protein modification
Introduce hydrogel-anchoring groups onto proteins and antibodies, with reagent options that also provide a label or tag for subsequent detection.
Detection suited to your workflow
Direct fluorescent, reactive-handle and biotin-based formats support different approaches to introducing and detecting the label.
Reagents for protein & antibody labelling
Find conjugation reagents and anchoring chemistry for your protein preparation, detection format and imaging workflow.
Explore related applications
Follow the next steps in preparing your labels, from hydrogel attachment to fluorescent detection after sample processing.
Biomolecule Anchoring & Retention
Explore the chemical connection between a biological target or label and the hydrogel, with anchoring approaches for different molecular groups.
Post-Expansion Labelling
Discover approaches that separate early target labelling and anchoring from the later introduction of fluorescent detection.
Let's talk about your experiment
Tell us about your work and what you’d like to achieve. We’re here to answer your labelling questions and help you choose the right reagents. We'd love to hear from you!